I plan on going with a slightly less dramatic overhaul, so my current plans are redoing the Afterbirth stages and then all stages past the Cathedral (excluding the Void). I decided to start from scratch with the Afterbirth+ version, so there will be a lot of missing content. Now, this version of Godmode is not the version that most of you are familiar with.
Items will stay unlocked until the final boss is deemed ready to be implemented.